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Acute brain injury (ABI) is common in venoarterial extracorporeal membrane oxygenation (VA-ECMO). One of the most common indications for use of VA-ECMO is postcardiotomy shock (PCS). The authors aimed to characterize the prevalence of ABI and its association with outcomes in this population. prospective observational. Single-center tertiary care university hospital. Fifty-two consecutive patients treated for PCS with VA-ECMO from November 2017 to March 2020. None. The median age of patients was 64 (interquartile range 44-84), 62% were