https://www.selleckchem.com/pr....oducts/wortmannin.ht
Individuals with Lynch syndrome (LS), have an increased risk of developing cancer. Common genetic variants of telomerase reverse transcriptase (TERT) have been associated with a wide range of cancers, including colorectal cancer (CRC) in LS. We combined genotype data from 1881 LS patients, carrying pathogenic variants in MLH1, MSH2 or MSH6, for rs2075786 (GA, intronic variant), 1207 LS patients for rs2736108 (CT, upstream variant) and 1201 LS patients for rs7705526 (CA, intronic variant). The risk of cancer was estimated
Like
Comment
Share
