https://www.selleckchem.com/pr....oducts/epz011989.htm
001 for all analyses). Compared with Rome III criteria, those with Rome IV IBS-type symptoms had significantly higher rates of anxiety (p0.001), depression (p=0.002), and somatization (p0.001), lower quality of life scores (p0.001) and were more likely to have CD (p=0.011), with ileal distribution (p=0.006). Rome IV IBS-type symptoms are associated with increased psychological co-morbidity, lower quality of life scores, and higher rates of antidepressant or opioid use. This is a cohort potentially at risk of adverse clinic
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