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This, in turn, would place a higher need on assistance systems from neighborhood astrocytes, which by themselves show necessary protein modifications that may affect their functionality. Taken together, this study highlights key processes that are modified with age in the rat SN, all of which converges upon GFAP. These conclusions provide understanding of the relationship between aging and increased difficulties to neuronal viability, and suggest an important role for glial cells within the process of gett

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