https://www.selleckchem.com/pr....oducts/PD-0332991.ht
Rather than being confined to a small number of distal elements or promoters, we find that genetic signals converge on congruently regulated sets of DHSs that decorate entire gene bodies. Together, our results create a universal, extensible coordinate system and vocabulary for human regulatory DNA marked by DHSs, and provide a new global perspective on the architecture of human gene regulation.The majority of therapies that target individual proteins rely on specific activity-modulating interactions with the target protein-for exampl