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ments if warranted. · One-third of infants on chlorothiazide develop hyponatremia.. · Nadir serum sodium typically occurs within 5 days.. · Monitor sodium closely after chlorothiazide initiation.. · One-third of infants on chlorothiazide develop hyponatremia.. · Nadir serum sodium typically occurs within 5 days.. · Monitor sodium closely after chlorothiazide initiation..  Low birth weight (LBW) infants (2,500 g) continued to be a global health problem because of the associated short- and long-term adverse outcomes. The study aimed to