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A highly hydrophilic POSS-based aptamer affinity monolith had been rapidly ready in 1.1 h, and a higher capacity of aptamer reached 2772.61 pmol/μL which was greater than that of the present POSS-based aptamer affinity monoliths. By in this way, the hydrophilic nature and aptamer coverage indensity in POSS monoliths were well enhanced. The mixed-mode method including aptamer affinity recognition and hydrophilic interaction had been employed for the particular analysis of ZEN. Applied to the tabs

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