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https://www.selleckchem.com/pr....oducts/pf-477736.htm
Potential mechanisms of action included the stimulation of caspase-dependent apoptotic pathway, inhibition of SHH pathway and decreased expression of SOX2 and OCT4. Combining SF allowed lower doses of CIS or 5-FU while enhancing these drug cytotoxicities against HNSCC-CSCs, with minimal effects on healthy cells. Combining SF allowed lower doses of CIS or 5-FU while enhancing these drug cytotoxicities against HNSCC-CSCs, with minimal effects on healthy cells. Oestrogen receptor (ER) in invasive breast cancer (BC) predicts response to e

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