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Background The investigation of serous effusions has an important place in cytopathology because it has diagnostic and prognostic value. The proper identification of the primary tumor with staging and grading has therapeutic and prognostic implications. In the current study, we evaluated the efficacy of two techniques for the diagnosis of malignant serous effusions. Methods Fresh samples of pleural, peritoneal, and pericardial fluids were evaluated for the present study. Ten milliliters of fluid were divided into two equal parts of 5 m
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