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falciparum. In addition, from the eight Malaria Box compounds tested in both species, compounds MMV665830, MMV665878 and MMV665941 were selected as a hit compounds due the high inhibition observed. Our results showed that P. berghei is suitable as an initial screening system to test compounds against P. vivax. Our results showed that P. berghei is suitable as an initial screening system to test compounds against P. vivax. The coronaviruses (CoVs) called the attention of the world for causing outbreaks of severe acute respiratory syndrome (SARS-CoV),