https://www.selleckchem.com/
Yet, anatomy, neurotoxic lesions, and optogenetic manipulation implicate the NAcc in threat. Here, we directly revealed NAcc threat firing by recording single-unit activity during multi-cue fear discrimination. Most cue-responsive NAcc neurons markedly altered firing to threat cues. Finer analyses revealed a NAcc population signaling threat specifically decreasing firing to danger and uncertainty cues; and a NAcc population signaling bidirectional valence increasing firing to reward but decreasing firing to the danger cue. The results reveal the NAcc to be