https://www.selleckchem.com/pr....oducts/pf-2545920.ht
Clopidogrel treatment prevented silica-induced changes in lung function, and significantly reduced lung inflammation, fibrosis, as well as cytokine and nitrite production. These data suggest that inhibition of P2Y12 signaling improves silica-induced lung inflammation, preventing lung functional changes and mortality. Our results corroborate previous observations of silica-induced lung changes and expand the understanding of purinergic signaling in this process. Copyright © 2020 Santana, Luna-Gomes, Rangel-Ferreira, Tamura, Da Graça,
Like
Comment
Share
