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The mass media are relevant in shaping the population's attitudes towards mental disorders. In low- and middle-income countries there is little information about the portrayal of people with mental disorders in the mass media. The general objective of the study was to assess the tone and content of Chilean newspaper articles about mental disorder from 2000 to 2019. The digital editions of four national circulation Chilean newspapers were intentionally selected. The search engine Google News was used to identify and retrieve the news. To