https://www.selleckchem.com/pr....oducts/iclepertin.ht
It is known that the relative costs of different alleles are environmentally dependent, but our results also demonstrate that the relative fitness of given alleles depends on which alleles are present in a given population, as previous pairwise comparisons of allele fitness do not exactly match (except for super-kdr) the results obtained using this four allele study. The fitness cost associated with the super-kdr allele is consistent with previous reports and appears to be a factor in helping to restrain high levels of resistance in
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