https://www.selleckchem.com/pr....oducts/crenolanib-cp
e, does this by generating inclusion bodies in the cytoplasm of infected cells. We confirm that both bRSV and human RSV viral RNA replication takes place in these inclusion bodies, likely meaning these organelles are a functionally conserved feature of this group of viruses (the orthopneumoviruses). Importantly, we also showed that these organelles are able to capture important innate immune transcription factors (in this case NF-K, blocking the normal signaling processes that tell the nucleus the cell is infected, which
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