https://www.selleckchem.com/pr....oducts/gsk3326595-ep
We want to explore the changing law of circulating histones in the acute stage of urosepsis and to find more sensitive and specific biomarkers for diagnosing urosepsis as early as possible. Twenty healthy male New Zealand rabbits were randomly divided into 4 groups ( = 5) the control group, sham group, model group of LPS 600  g/kg, and model group of LPS 1000  g/kg. Heart rate (HR), respiration rate (RR), rectal temperature (T), and mean arterial pressure (MAP) were examined at 1, 3, 6, 12, and 24 hours after operation. Bes