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50; 95% CI -0.90, -0.1 aged ≥65 years; however, a similar association was not observed in younger participants. Low HGS was associated with albuminuria in older men and women in Japan. Low HGS was associated with albuminuria in older men and women in Japan.The Guaraní Aquifer System (SAG) is the largest transboundary aquifer in Latin America, extending beneath parts of Brazil, Paraguay, Argentina, and Uruguay. This paper presents the results of recent hydrogeological studies in the southern portion of the SAG. Locally, the abundance