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88, and accuracy 0.86) and prosody-related features for females (sensitivity 0.73, specificity 0.86, and accuracy 0.77). The correlation distance between negative and positive MIS was significantly shorter in the depressed group than in the healthy control (F=18.574, P 0.001). Small sample size and relatively homogenous clinical profile of depression could limit the generalizability. While reading MIS, spectral and energy-related acoustic features for males and prosody-related features for females are good discriminators for major
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