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Technological and computational advancements offer new tools for the collection and analysis of real-world data (RWD). Considering the substantial effort and resources devoted to collecting RWD, a greater return would be achieved if real-world evidence (RWE) was effectively used to support Health Technology Assessment (HTA) and decision making on medical technologies. A useful question is To what extent are RWD suitable for generating RWE? We mapped existing RWD sources in Europe for three case studies hip and knee arthroplasty, transca
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