https://ogg1signaling.com/inde....x.php/brilliant-and-
In EMPA treated murine hearts, CD31/VEGFR2 positive endothelial cells and also the pSTAT-3(Y705) sign produced by endothelial cells had been boosted at early reperfusion. DEVELOPMENT Chronic EMPA administration reduces IS in healthy mice via STAT-3 pathway and increased survival of endothelial cells. CONCLUSION Chronic yet not acute administration of EMPA reduces IS through STAT-3 activation independently of diabetes
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