https://www.selleckchem.com/pr....oducts/ionomycin.htm
Physcion (Phy) exerts several pharmacological effects including anti-inflammatory, antioxidant, and antitumor properties. This study investigates the cytotoxicity and its underlying mechanisms of Phy on breast cancer. Human breast cancer cell MCF-7 was treated with 5-400 µM Phy for 24 h, MCF-7-xenografted BALB/c nude mice and immunosuppressive mice model induced by cyclophosphamide were intraperitoneally injected with 0.1 mL/mouse normal saline (control group) and 30 mg/kg Phy every other day for 14 or 28 days, and pathological examin