https://www.selleckchem.com/pr....oducts/Sodium-orthov
Administration of NS309 immediately before and during CP hypoxia significantly improved the recovery of coronary endothelial function, as demonstrated by increased relaxation responses to adenosine 5'-diphosphate and substance P compared with those seen in controls (P less then .05). This protective effect was more pronounced in vessels from ND mice and patients compared with DM mice and patients (P less then .05). Cell surface membrane SK3 expression was significantly reduced after hypoxia, whereas cytosolic SK3 expression
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