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7 and 7.8 mg L-1; all of which were above the WHO recommended level of fluoride (0.8-1.5 mg L-1) in drinking water. This method can potentially be used for total fluorine determination and might be useful for fluorine speciation analysis when coupled with HPLC.Surface-enhanced Raman spectroscopy, due to its high sensitivity, unique vibrational fingerprint identification of molecules and easy operation, has been extensively applied in different fields. Aptamers, being the unique single stranded DNA/RNA sequences that can specifically re

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