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Under optimal experimental conditions the linear detection ranges were found to be 0.05-50.00 μg L-1 with limits of detection calculated from a blank test, based on 3σ, 0.02-0.04 μg L-1. Recovery values in the range of 85-105% were achieved for tea infusion with a reproducibility expressed as RSD less than 4.1%.In this work, for the first time, chromatographic paper was used for a multiphase extraction assisted by an electric field (MPEF) and directly coupled to paper spray mass spectrometry (PS-MS). Using this approach, five tricyclic antidepressants (TCAs

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