https://www.selleckchem.com/pr....oducts/ndi-091143.ht
Long-term survivors of craniospinal irradiation have an increased risk for stroke which increases with radiation dose and follow-up time. Radiotherapy induces structural changes of the cerebral vasculature, affecting both, large, and small vessels. It is unknown how these structural changes affect functional mechanisms of cerebral blood flow regulation such as cerebral autoregulation and neurovascular coupling. Using the transcranial Doppler, we compared dynamic cerebral autoregulation and neurovascular coupling of 12 patients after