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Salmonella Heidelberg the most typical serovar causing foodborne ailments. To reduce growth of digestive bacterial infection, dietary supplements containing probiotic micro-organisms is suggested. Commensal non-toxigenic Bacteroides fragilis has been suggested as a next-generation probiotic prospect. By utilizing an authentic triple co-culture model including Caco-2 cells (representing person enterocytes), HT29-MTX (representing mucus-secreting goblet cells), and M cells differentiated