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25% and 0.25%; Pearson's correlation coefficients were 0.93 and 0.93; percentages of eA1c within 10% from reference HbA1c were 97.6% and 96.3%, respectively. Conclusions HbA1c and TIR are reflections of the same underlying process of glycemic fluctuation. Using a model individualized with one HbA1c measurement, TIR provides an accurate approximation of HbA1c for at least 6 months, reflecting BG fluctuations and non-glycemic biological factors. Thus, eA1c is an intermediate metric that mathematically adjusts a CGM-based assessment of gly

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