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A multivariable-adjusted model revealed that patients in Q1 had a significantly higher odds ratio (95% confidence interval) for bone fracture history than those in Q4 (reference) Q1, 2.77 (1.32-5.8; Q2, 1.95 (1.05-3.65); and Q3, 1.57 (0.90-2.75) (P-value for trend less then 0.001). Similar associations were obtained when other skeletal muscle surrogates were applied serum creatinine to serum cystatin C and daily urinary creatinine excretion. These results suggest that a lower eSMM is associated with an increased prevalence of histor
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