https://www.selleckchem.com/products/pt2399.html
The degradation ratio of gelsenicine in liver microsomes decreased in the following order PLM≥GLMHLMRLM. The production of M1 decreased in the order of GLMPLMRLMHLM, the production of M2 was similar among the four species, and the production of M3 was higher in the HLM than in the liver microsomes of the other three species. Conclusions Based on these results, demethylation was speculated to be the main gelsenicine detoxification pathway, providing vital information to better understand the metabolism and toxicity dif
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