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Extremely these early behavioural deficits are followed by aberrant plasticity at synapses between engine cortex and dorsal striatum. This research not only provides a better understanding into the synaptopathic systems of HD, but also highlights that deficit in motor skill consolidation-dependent synaptic plasticity at motor cortex to dorsal striatum synapses presents an early on biomarker for Huntington's illness. Copyright © 2020 Glangetas et al.There will not be an impo

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