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We tested the effect of voluntary running exercise after chronic diet-induced obesity on knee OA-related cartilage and bone pathology in mice. We then utilized a correlation-based community analysis to recognize systemic and regional aspects connected with early-stage leg OA phenotypes among the list of various diet and exercise teams. Practices Male C57BL/6J mice were provided a precise control (10% kcal fat) or high fat (HF) (60% kcal fat) diet from 6 to 37 months of age. At 25 days, one-half r
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