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As per Gidding's statistical overlap theory, peak overlap cannot be avoided for a completely random sample for a column with a given peak capacity. Signal processing techniques based on Fourier transform deconvolution of band broadening, power laws, derivatives, and iterative curve fitting are explained to help improve the chromatographic resolution. An example of ten peaks separated in under a second is shown and discussed. Other ultrafast separations in supercritical fluid chromatography or capillary electrophoresis are briefly mentioned

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