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The Pearson correlation coefficient between medians of PFS and OS ended up being 0.84 (95% confidence period (CI) 0.68-0.92, p less then 0.001), together with correlation coefficient between HRPFS and HROS ended up being 0.86 (95% CI 0.63-0.95, p less then 0.001). Weighted multiple regression evaluation showed HRPFS ended up being the most important predictor of HROS among covariates analyzed (p less then 0.001). Both the medians of PFS and OS correlation, together with HRPFS and HROS correl