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https://www.selleckchem.com/pr....oducts/4-Methylumbel
In this paper we investigated a new method for dose-response analysis of longitudinal data in terms of precision and accuracy using simulations. The new method, called Dose-Response Mixed Models for Repeated Measures (DR-MMRM), combines conventional Mixed Models for Repeated Measures (MMRM) and dose-response modeling. Conventional MMRM can be applied for highly variable repeated measure data and is a way to estimate the drug effect at each visit and dose, however without any assumptions regarding the dose-response sh

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