https://cp21inhibitor.com/from....-problem-recognition
We report the selective targeting of telomeric G4 DNA with a dithienylethene ligand and demonstrate the robust visible-light mediated flipping of this G4 ligand binding mode and G-tetrad construction in physiologically-relevant problems. The poisoning regarding the ligand to cervical disease cells is modulated by the photoisomeric state associated with the ligand, indicating for the first time the possibility of G4 to act as a target for photopharmacological techniques.We have, for the first ti
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