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Under problems of pharmacologically improved monoamine endogenous tone, GPR139 KO mice revealed a blunted response to citalopram or fluoxetine induced REM sleep suppression and an attenuated response to the aftermath marketing effect of amphetamine. These results indicate an emerging role of GPR139 within the modulation of sleep states.Background Transit-time flow measurement (TTFM) is often used for intraoperative graft circulation analysis during coronary artery bypass grafting (CABG). Althoug