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TNF is a crucial cytokine for the pathogenesis of several rheumatic conditions, as well as its inhibition is a mainstay of treatment to manage joint signs, including discomfort. Right here, we sought to research the inflammatory modifications as well as the part of TNF in dorsal root ganglia (DRG) during persistent hypernociception following the resolution of severe joint infection. Using a model of antigen-induced arthritis, the top of shared inflammation happened

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