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Hodor-like genes are insect-specific, and may represent targets for the control of disease vectors. Indeed, CRISPR-Cas9 genome editing revealed that the single hodor orthologue in Anopheles gambiae is an essential gene. Our findings highlight the need to consider the instructive contributions of metals-and, more generally, micronutrients-to energy homeostasis.An amendment to this paper has been published and can be accessed via a link at the top of the paper.The ID complex, involving the proteins FANCI and FANCD2, is required for the rep
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