https://www.selleckchem.com/pr....oducts/Vorinostat-sa
05). PSE-NB improved mRNA expression of tight junction proteins (ZO-1 and Occludin) and NHE3, which were reduced by LPS stimulation (p0.05). Moreover, PSE-NB (10μg/mL) alleviated LPS-induced protein expression of p65 and p-p65 (p0.05), and reduced p65 translocation into the nucleus induced by LPS. At the same time, metabolic pathway analysis indicated that PSE-NB exerts anti-inflammatory effects mainly via augmentation of methionine metabolism in IPEC-J2 cells. Taken together, the results suggested that alkaloids and phe
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