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© 2020 Water Environment Federation PRACTITIONER POINTS Sediment capping technology continues to advance Sampling and testing methods continue to be refined Natural processes such as biodegradation are being better understood Beneficial use of dredged sediment continue to be emphasized.As a unique structural moiety in natural products, cinnamoyl lipids (CLs), are proposed to be assembled by unusual type II polyketide synthases (PKSs). Herein, we demonstrate that the assembly of the CL compounds youssoufenes is accomplished by a PKS syst