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and are proteolytic periodontopathogens that co-localize in polymicrobial subgingival plaque biofilms, display growth symbiosis and synergistic virulence in animal models of disease. These symbioses are underpinned by a range of metabolic interactions including cooperative hydrolysis of glycine-containing peptides to produce free glycine, which uses as a major energy and carbon source. To characterize the gene products essential for these interactions. MethodsThe transcriptome exposed to cell-free conditioned medium was determined usin
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