https://www.selleckchem.com/pr....oducts/Cyclopamine.h
hinders OPC maturation. Subsequently, A1 astrocytes inhibit microglial phagocytosis of myelin debris via an astrocytic C3-microglial C3aR axis. Polyethylene glycol-CeNP treatment inhibits this pathological process and ultimately promotes remyelination. Such findings enlighten us that astrocytes and microglia should be regarded as a functional unit in future works. The present study reveals a new mechanism in white matter injury after ICH ICH induces M1 microglia and A1 astrocyte through ROS-induced NF-κB p65 translocation that hinde
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