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When CN was compared to healthy controls or diabetics, the difference was more prominent for healthy controls (SDM = 1.043, 95%CI = 0.676-1.409, p  0.001) than diabetics (SDM = 0.639, 95%CI = 0.456-0.821, p  0.001) and the SDM difference was significant (p = 0.013). Using 6 publications (9 studies), neither the 1181C  G or the 950T  C polymorphisms showed any significant associations for any genetic model. For the 245A  C polymorphism, only the homozygous genetic model showed a significant association between the poly

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