https://www.selleckchem.com/pr....oducts/pf-06826647.h
04). GATA3 expression was higher in tumors than normal tissues. Several pathways were different between mutant and non-mutant groups (p less then 0.05). Interleukin-6 was found as the highest scored gene in both comparisons (normal vs. mutant and normal vs. non-mutant groups) in the entire patient and in the ER-positive subgroup, suggesting the association of IL6 with breast tumorigenesis. These findings suggest that GATA3 mutations can be associated with several tumor characteristics and influence the pattern of gene expression.
Like
Comment
Share
