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Simulated At-MABG doses from I-MIBG using the RAP method were in agreement with those from At-MABG, so that their boxes overlapped in the box plots. The RAP method showed applicability to the different cell lines, but it was difficult to predict long-term doses from short-term experimental data. The present RAP dose conversion method could estimate At-MABG absorbed doses from the pharmacokinetics of I-MIBG with some limitations. The RAP method would be applicable to a large number of subjects for targeted nuclide therapy. The present RAP
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