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Inclusion criteria were a medical diagnosis of OL; biopsy excision; and observance for at the least 12months into the ORA-LEU-CAN study. In the very first visit, most of the customers had been asked about the incident of symptoms in the lesion. Ninety-four topics had been considered during a period of 1year. All patients underwent complete elimination of OL. The patient cohort had been split into three sub-groups (i) no discomfort before excision as well as the 1-yea
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