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In addition, the evaluation of histopathological and immunohistochemical PCNA expression showed significant variations in the liver that confirm the biochemical results. Administration of REO pre- or post-chromium treatment restored the parameters cited above near to the normal values. Otherwise, individual intake with REO slumped lipid peroxidation and gotten better antioxidant status significantly. Conclusively, REO proved to be an effective antioxidant in modulating Cr VI-induced hepatotoxicity, especially in the pretreated rats.The ac
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