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Nonetheless, the role and device of 6-gingerol along the way of VILI is not clearly investigated. Into the study, we discovered that pre-treatment with 6-gingerol substantially enhanced the histological changes and pulmonary oedema, inhibited neutrophil accumulation while the release of very early pro-inflammatory cytokines and MPO, and reduced oxidative anxiety reactions after high MV. More over, 6-gingerol treatment additionally increased PPARγ expression and reduced NF-κB activation in rats afflicted by high MV. Moreover, GW96
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