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What Happens If ADHD is Left Untreated in Adults? Adults with ADHD can experience a range of problems if the condition is not treated. These include problems with relationships, work and mental health. Adults suffering from untreated ADHD typically have low self-esteem, and have a negative outlook on the world. This can make them feel as if they are failing in their work and at home. Lack of Focus It is normal to have trouble focusing from time-to-time, especially after a busy day at school or work. If you begin to notice that your concentration has been decreasi