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04 increase in the EDSS for each 1-μm decrease in the baseline GCIPL, 95% confidence interval 0.006-0.08; P = 0.02). The baseline GCIPL was thinner in patients with RRMS with FU-EDSS 4 compared with those with FU-EDSS ≤4, and individuals in the highest baseline GCIPL tertile had a significantly lower FU-EDSS score than those in the middle and lowest tertile (P = 0.01 and P = 0.001, respectively). These findings were not confirmed in analyses restricted to patients with PMS. Among OCT-derived metrics, GCIPL thickness had the stronges
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